Article
Conserved Streptococcus pneumoniae Spirosomes Suggest a Single Type of Transformation Pilus in Competence
15 Apr 2015
Abstract excerpt
The success of S. pneumoniae as a major human pathogen is largely due to its remarkable genomic plasticity, allowing efficient escape from antimicrobials action and host immune response. Natural transformation, or the active uptake and chromosomal integration of exogenous DNA during the transitory differentiated state competence, is the main mechanism for horizontal gene transfer and genomic makeover in...
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