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Secretion of a pneumococcal type II secretion system pilus correlates with DNA uptake during transformation

3 Feb 2014

Abstract excerpt

Streptococcus pneumoniae is a major human pathogen that successfully adapts to the host environment via an efficient uptake system for free DNA liberated from other organisms in the upper respiratory tract, facilitating immune evasion and drug resistance. Although the initial signaling events leading to pneumococcal competence for DNA transformation and the fate of DNA when it has been taken up have been...

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PMID: 24550320
DOI: 10.1073/pnas.1313860111

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