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Article

Pharmacogenetic and case-control study on potassium channel related gene variants and genetic generalized epilepsy.

Medicine - 1 Jun 2017

Qu Jian, Lu Shao-Hua, Lu Zhi-Li, Xu Ping, Xiang Da-Xiong, Qu Qiang

Abstract excerpt

Potassium channels are the targets of antiepileptic drugs (AEDs), which play important roles in the etiology of epilepsy. KCNA1 and KCNA2 encode mammalian Kv1.1 and Kv1.2 channels, which are essential roles in the initiation and shaping of action potentials. KCNV2 encodes Kv8.2, which is a regional overlap with Kv2 subunits as functional heterotetramers. In our study, we aim to investigate whether variants of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Genotyping Techniques

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Share to Potassium Channels, Voltage-Gated

Source

Open in PubMed Open full text

Identifiers

PMID: 28658141
DOI: 10.1097/MD.0000000000007321
PMCID: PMC5500063

Genes

KCNA1
KCNA2
KCNV2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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