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Article

The role of the immune system in triplet repeat expansion diseases.

Mediators of inflammation - 1 Jan 2015

Olejniczak Marta, Urbanek Martyna O, Krzyzosiak Wlodzimierz J

Abstract excerpt

Trinucleotide repeat expansion disorders (TREDs) are a group of dominantly inherited neurological diseases caused by the expansion of unstable repeats in specific regions of the associated genes. Expansion of CAG repeat tracts in translated regions of the respective genes results in polyglutamine- (polyQ-) rich proteins that form intracellular aggregates that affect numerous cellular activities. Recent evidence...

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Identifiers

PMID: 25873774
DOI: 10.1155/2015/873860
PMCID: PMC4385693

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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