Article
GAS6 intron 8 c.834 + 7G > A gene polymorphism in diabetic nephropathy.
Renal failure - 1 Jun 2015
Erkoc Reha, Cikrikcioglu Mehmet Ali, Aintab Emre, Toprak Aybala Erek, Kilic Ulkan, Gok Ozlem, Cetin Ayse Irem Yasin, Zorlu Mehmet, Kiskac Muharrem, Cakirca Mustafa, Erkal Sena Nur, Isen Hayati Can, Karatoprak Cumali
Abstract excerpt
UNLABELLED: BACKGROUND - AIM: In animal experiments, growth arrest-specific 6 (Gas6) protein plays a key role in the development of mesangial cell and glomerular hypertrophy in the early phase of diabetic nephropathy, and diabetic nephropathy is prevented by warfarin-induced inhibition of GAS6 protein. It was shown that GAS6 intron 8 c.834 + 7G > A polymorphism is protective against type 2 diabetes mellitus, and...
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