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Article

EGFR gene polymorphisms -216G>T and -191C>A are risk markers for gastric cancer in Mexican population.

Genetics and molecular research : GMR - 13 Mar 2015

Torres-Jasso J H, Marín M E, Santiago-Luna E, Leoner J C, Torres J, Magaña-Torres M T, Perea F J, Ibarra B, Sánchez-López J Y

Abstract excerpt

Epidermal growth factor receptor (EGFR) is a transmembrane glycoprotein with tyrosine-kinase activity that plays an important role in multiple cellular functions. EGFR overexpression has been observed in several types of tumors and it is significantly associated with disease stage, survival, prognosis, and progression of cancer. The polymorphisms -216G>T, -191C>A, and (CA)n first intervening sequence (IVS1) have...

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Identifiers

PMID: 25867325
DOI: 10.4238/2015.March.13.8

Genes

EGFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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