Article
Hypoxia induced high expression of thioredoxin interacting protein (TXNIP) in non-small cell lung cancer and its prognostic effect.
Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2015
Li Yan, Miao Li-Yun, Xiao Yong-Long, Huang Mei, Yu Min, Meng Kui, Cai Hou-Rong
Abstract excerpt
Although associations between thioredoxin interacting protein (TXNIP) and cancers have been recognized, the effects of TXNIP on non-small cell lung cancer (NSCLC) prognosis remained to be determined in detail. In addition, while hypoxia is a key characteristic of tumor cell growth microenvironment, the effect of hypoxia on TXNIP expression is controversial. In this study, formaldehyde fixed and paraffin embedded...
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