Article
[The association of polymorphisms in SLC18A1, TPH1 and RELN genes with risk of paranoid schizophrenia].
Molekuliarnaia biologiia - 1 Jan 2000
Galaktionova D Iu, Gareeva A E, Khusnutdinova E K, Nasedkina T V
Abstract excerpt
We have developed a biochip for the analysis of polymorphisms in candidate genes for schizophrenia: DISC1, RELN, ZNF804A, PLXNA2, COMT, SLC18A41, CACNA1C, ANK3, TPH1, PLAA and SNAP-25. Using biochip the allele and genotype frequencies in 198 patients with schizophrenia and 192 healthy individuals have been obtained. For SLC18A1 polymorphism rs2270641 A>C, the frequencies of A allele (p = 0.007) and AA genotype (p...
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