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Article

Plant biology. Suppression of endogenous gene silencing by bidirectional cytoplasmic RNA decay in Arabidopsis.

Science (New York, N.Y.) - 3 Apr 2015

Zhang Xinyan, Zhu Ying, Liu Xiaodan, Hong Xinyu, Xu Yang, Zhu Ping, Shen Yang, Wu Huihui, Ji Yusi, Wen Xing, Zhang Chen, Zhao Qiong, Wang Yichuan, Lu Jian, Guo Hongwei

Abstract excerpt

Plant immunity against foreign gene invasion takes advantage of posttranscriptional gene silencing (PTGS). How plants elaborately avert inappropriate PTGS of endogenous coding genes remains unclear. We demonstrate in Arabidopsis that both 5'-3' and 3'-5' cytoplasmic RNA decay pathways act as repressors of transgene and endogenous PTGS. Disruption of bidirectional cytoplasmic RNA decay leads to pleiotropic...

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PMID: 25838384
DOI: 10.1126/science.aaa2618

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