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Article

IL28B polymorphism correlates with active hepatitis in patients with HBeAg-negative chronic hepatitis B.

PloS one - 1 Jan 2013

Lee I-Cheng, Lin Chen-Hao, Huang Yi-Hsiang, Huo Teh-Ia, Su Chien-Wei, Hou Ming-Chih, Huang Hui-Chun, Lee Kuei-Chuan, Chan Che-Chang, Lin Ming-Wei, Lin Han-Chieh, Lee Shou-Dong

Abstract excerpt

BACKGROUND AIMS: The clinical relevance of single nucleotide polymorphisms (SNPs) near the IL28B gene is controversial in patients with hepatitis B virus (HBV) infection. This study aimed to investigate the role of viral and host factors, including IL28B genotypes, in the natural course of chronic hepatitis B (CHB). METHODS: The study enrolled consecutive 115 treatment-naive CHB patients. HBV viral loads,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 23469142
DOI: 10.1371/journal.pone.0058071
PMCID: PMC3585285

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