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Article

Signal transduction in cancer.

Cold Spring Harbor perspectives in medicine - 1 Apr 2015

Sever Richard, Brugge Joan S

Abstract excerpt

Cancer is driven by genetic and epigenetic alterations that allow cells to overproliferate and escape mechanisms that normally control their survival and migration. Many of these alterations map to signaling pathways that control cell growth and division, cell death, cell fate, and cell motility, and can be placed in the context of distortions of wider signaling networks that fuel cancer progression, such as...

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Identifiers

PMID: 25833940
DOI: 10.1101/cshperspect.a006098
PMCID: PMC4382731

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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