Article
Insight into neutral and disease-associated human genetic variants through interpretable predictors.
PloS one - 1 Jan 2015
van den Berg Bastiaan A, Reinders Marcel J T, de Ridder Dick, de Beer Tjaart A P
Abstract excerpt
A variety of methods that predict human nonsynonymous single nucleotide polymorphisms (SNPs) to be neutral or disease-associated have been developed over the last decade. These methods are used for pinpointing disease-associated variants in the many variants obtained with next-generation sequencing technologies. The high performances of current sequence-based predictors indicate that sequence data contains...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.