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Role of uropathogenic Escherichia coli outer membrane protein T in pathogenesis of urinary tract infection

21 Jan 2015

Abstract excerpt

OmpT is one of the members of the outer membrane protein family that has been identified as a virulence factor in most of the uropathogenic Escherichia coli (UPEC). However, the exact role of OmpT in the urinary tract infections (UTIs) remains unclear. To determine the role of OmpT in the pathogenesis of UPEC, an isogenic deletion mutant of ompT (COTD) was constructed by the λ Red recombination. Human bladder...

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PMID: 25825479
DOI: 10.1093/femspd/ftv006

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