Evaluation of weight loss and metabolic changes in diabetic patients treated with liraglutide, effect of RS 6923761 gene variant of glucagon-like peptide 1 receptor.

doi:10.1016/j.jdiacomp.2015.02.010

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Article

Evaluation of weight loss and metabolic changes in diabetic patients treated with liraglutide, effect of RS 6923761 gene variant of glucagon-like peptide 1 receptor.

Journal of diabetes and its complications - 1 Jan 2000

de Luis Daniel Antonio, Diaz Soto Gonzalo, Izaola Olatz, Romero Enrique

Abstract excerpt

BACKGROUND: A polymorphism of GLP-1 R (rs6923761) has potential implications in weight loss and metabolic control. We decide to investigate the role of this polymorphism on metabolic changes and weight loss secondary to treatment with liraglutide. MATERIAL AND METHODS: A population of 90 patients with diabetes mellitus type 2 and overweight, unable to achieve glycemic control (HbA1c>7%) with metformin alone that...

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PMID: 25825013
DOI: 10.1016/j.jdiacomp.2015.02.010

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