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Article

Association of NADPH oxidase polymorphisms with anthracycline-induced cardiotoxicity in the RICOVER-60 trial of patients with aggressive CD20(+) B-cell lymphoma.

Pharmacogenomics - 1 Jan 2015

Reichwagen Annegret, Ziepert Marita, Kreuz Markus, Gödtel-Armbrust Ute, Rixecker Tanja, Poeschel Viola, Reza Toliat Mohammad, Nürnberg Peter, Tzvetkov Mladen, Deng Shiwei, Trümper Lorenz, Hasenfuss Gerd, Pfreundschuh Michael, Wojnowski Leszek

Abstract excerpt

AIM: To identify gene variants responsible for anthracycline-induced cardiotoxicity. PATIENTS & METHODS: Polymorphisms of the NADPH oxidase subunits and of the anthracycline transporters ABCC1, ABCC2 and SLC28A3 were genotyped in elderly patients (61-80 years) treated for aggressive CD20(+) B-cell lymphomas with CHOP-14 with or without rituximab and followed up for 3 years. RESULTS: The accumulation of RAC2...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 25823784
DOI: 10.2217/pgs.14.179

Genes

RAC2
ABCC1
ABCC2
CYBA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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