Article
Model-independent phenotyping of C. elegans locomotion using scale-invariant feature transform.
PloS one - 1 Jan 2015
Koren Yelena, Sznitman Raphael, Arratia Paulo E, Carls Christopher, Krajacic Predrag, Brown André E X, Sznitman Josué
Abstract excerpt
To uncover the genetic basis of behavioral traits in the model organism C. elegans, a common strategy is to study locomotion defects in mutants. Despite efforts to introduce (semi-)automated phenotyping strategies, current methods overwhelmingly depend on worm-specific features that must be hand-...
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