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Article

Comparative genomic analysis reveals a critical role of de novo nucleotide biosynthesis for Saccharomyces cerevisiae virulence.

PloS one - 1 Jan 2015

Pérez-Torrado Roberto, Llopis Silvia, Perrone Benedetta, Gómez-Pastor Rocío, Hube Bernhard, Querol Amparo

Abstract excerpt

In recent years, the number of human infection cases produced by the food related species Saccharomyces cerevisiae has increased. Whereas many strains of this species are considered safe, other 'opportunistic' strains show a high degree of potential virulence attributes and can cause infections in immunocompromised patients. Here we studied the genetic characteristics of selected opportunistic strains isolated...

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Identifiers

PMID: 25816288
DOI: 10.1371/journal.pone.0122382
PMCID: PMC4376706

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