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Article

ClC-K chloride channels: emerging pathophysiology of Bartter syndrome type 3.

American journal of physiology. Renal physiology - 15 Jun 2015

Andrini Olga, Keck Mathilde, Briones Rodolfo, Lourdel Stéphane, Vargas-Poussou Rosa, Teulon Jacques

Abstract excerpt

The mutations in the CLCNKB gene encoding the ClC-Kb chloride channel are responsible for Bartter syndrome type 3, one of the four variants of Bartter syndrome in the genetically based nomenclature. All forms of Bartter syndrome are characterized by hypokalemia, metabolic alkalosis, and secondary hyperaldosteronism, but Bartter syndrome type 3 has the most heterogeneous presentation, extending from severe to very...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 25810436
DOI: 10.1152/ajprenal.00004.2015

Genes

CLCNKB

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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ClC-K chloride channels: emerging pathophysiology of Bartter syndrome type 3.PMID 25810436Read ↗

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