Article
Cardiac electrophysiological substrate underlying the ECG phenotype and electrogram abnormalities in Brugada syndrome patients.
Circulation - 2 Jun 2015
Zhang Junjie, Sacher Frédéric, Hoffmayer Kurt, O'Hara Thomas, Strom Maria, Cuculich Phillip, Silva Jennifer, Cooper Daniel, Faddis Mitchell, Hocini Mélèze, Haïssaguerre Michel, Scheinman Melvin, Rudy Yoram
Abstract excerpt
BACKGROUND: Brugada syndrome (BrS) is a highly arrhythmogenic cardiac disorder, associated with an increased incidence of sudden death. Its arrhythmogenic substrate in the intact human heart remains ill-defined. METHODS AND RESULTS: Using noninvasive ECG imaging, we studied 25 BrS patients to characterize the electrophysiological substrate and 6 patients with right bundle-branch block for comparison. Seven...
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