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Article

ABCG2 Localizes to the Nucleus and Modulates CDH1 Expression in Lung Cancer Cells

1 Mar 2015

Abstract excerpt

Breast cancer resistance protein [BCRP/ATP-binding cassette subfamily G member 2 (ABCG2)] is a member of the ATP-binding cassette transporter family. The presence of ABCG2 on the plasma membrane in many kinds of human cancer cells contributes to multidrug resistance during chemotherapy, and it has been used as the side population marker for identifying cancer stem cells in lung cancers. We report here that, in...

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PMID: 25810011
DOI: 10.1016/j.neo.2015.01.004

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