Article
Identifying disease candidate genes via large-scale gene network analysis.
International journal of data mining and bioinformatics - 1 Jan 2014
Kim Haseong, Park Taesung, Gelenbe Erol
Abstract excerpt
Gene Regulatory Networks (GRN) provide systematic views of complex living systems, offering reliable and large-scale GRNs to identify disease candidate genes. A reverse engineering technique, Bayesian Model Averaging-based Networks (BMAnet), which ensembles all appropriate linear models to tackle uncertainty in model selection that integrates heterogeneous biological data sets is introduced. Using network...
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