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Article

An approach to infer putative disease-specific mechanisms using neighboring gene networks.

Bioinformatics (Oxford, England) - 1 Jul 2017

Ansari Sahar, Donato Michele, Saberian Nafiseh, Draghici Sorin

Abstract excerpt

MOTIVATION: The ultimate goal of any experiment is to understand the biological phenomena underlying the condition investigated. This process often results in genes network through which a certain biological mechanism is explained. Such networks have been proven to be extremely useful, for the prediction of mechanisms of action of drugs or the responses of an organism to a specific impact (e.g. a disease, a...

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PMID: 28200075
DOI: 10.1093/bioinformatics/btx097
PMCID: PMC5870849

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