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Article

Spectacle: fast chromatin state annotation using spectral learning.

Genome biology - 12 Feb 2015

Song Jimin, Chen Kevin C

Abstract excerpt

Epigenomic data from ENCODE can be used to associate specific combinations of chromatin marks with regulatory elements in the human genome. Hidden Markov models and the expectation-maximization (EM) algorithm are often used to analyze epigenomic data. However, the EM algorithm can have overfittin...

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Identifiers

PMID: 25786205
DOI: 10.1186/s13059-015-0598-0
PMCID: PMC4355146

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Prepared record publication-25786205-2026-09-05.1. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 5 Sept 2026.

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