The Molecular Feature of HOX Gene Family in the Intramedullary Spinal Tumors

Abstract excerpt

STUDY DESIGN: The expression of HOXB13 and HOXA9 proteins was detected. OBJECTIVE: The purpose of this study was to investigate the molecular signature of spinal ependymoma (EPN) and astrocytoma, 2 most common types of intramedullary spinal tumor. SUMMARY OF BACKGROUND DATA: Intramedullary spinal tumor is unusual. It leads to high neurological morbidity and mortality without treatment. Till now, its molecular...

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