Article
Genetic dissection of mycobacterial biofilms.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2015
Ojha Anil K, Jacobs William R, Hatfull Graham F
Abstract excerpt
Our understanding of the biological principles of mycobacterial tolerance to antibiotics is crucial for developing shorter anti-tuberculosis regimens. Various in vitro approaches have been developed to identify the conditions that promote mycobacterial persistence against antibiotics. In our laboratories, we have developed a detergent-free in vitro growth model, in which mycobacteria spontaneously grow at the...
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