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Article

Association of four CpG-SNPs in the vascular-related genes with coronary heart disease.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie - 1 Mar 2015

Xu Leiting, Chen Xiaoying, Ye Huadan, Hong Qingxiao, Xu Mingqing, Duan Shiwei

Abstract excerpt

Vascular-related gene polymorphism can affect the susceptibility of coronary heart disease. In current study, we aimed to evaluate the contribution of four vascular-related gene CpG-SNPs to coronary heart disease (CHD). A total of 784 angiography-proven CHD patients and 746 non-CHD controls were included in the current association study. The four CpG-SNPs (including VEGFA rs1005230, ACE rs4316, CST3 rs3827143 and...

Topics

Case-Control Studies
Coronary Disease
CpG Islands

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Female

Gene Expression Regulation

Genetic Predisposition to Disease

Genotype

Humans

Male

Polymorphism, Single Nucleotide

Source

Identifiers

PMID: 25776483
DOI: 10.1016/j.biopha.2015.01.014

Genes

ACE
AGTR1
CST3
VEGFA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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