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Article

Genome wide expression profiling of p53 regulated miRNAs in neuroblastoma

12 Mar 2015

Abstract excerpt

Restoration of the antitumor activity of p53 could offer a promising approach for the treatment of neuroblastoma. MicroRNAs (miRNAs) are important mediators of p53 activity, but their role in the p53 response has not yet been comprehensively addressed in neuroblastoma. Therefore, we set out to characterize alterations in miRNA expression that are induced by p53 activation in neuroblastoma cells. Genome-wide miRNA...

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PMID: 25762502
DOI: 10.1038/srep09027

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