Article
Association of the apolipoprotein E 2 allele with concurrent occurrence of endometrial hyperplasia and endometrial carcinoma.
Oxidative medicine and cellular longevity - 1 Jan 2015
Ivanova Tatiana I, Krikunova Ludmila I, Ryabchenko Nikolay I, Mkrtchyan Liana S, Khorokhorina Vera A, Salnikova Lyubov E
Abstract excerpt
Genes encoding proteins with antioxidant properties may influence susceptibility to endometrial hyperplasia (EH) and endometrial carcinoma (ECa). Patients with EH (n = 89), EH concurrent with ECa (n = 76), ECa (n = 186), and healthy controls (n = 1110) were genotyped for five polymorphic variants in the genes involved in metabolism of lipoproteins (APOE Cys112Arg and Arg158Cys), iron (HFE Cys282Tyr and His63Asp),...
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