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Article

Problems with the nested granularity of feature domains in bioinformatics: the eXtasy case.

BMC bioinformatics - 1 Jan 2015

Popovic Dusan, Sifrim Alejandro, Davis Jesse, Moreau Yves, De Moor Bart

Abstract excerpt

BACKGROUND: Data from biomedical domains often have an inherit hierarchical structure. As this structure is usually implicit, its existence can be overlooked by practitioners interested in constructing and evaluating predictive models from such data. Ignoring these constructs leads to potentially problematic and the routinely unrecognized bias in the models and results. In this work, we discuss this bias in...

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PMID: 25734591
DOI: 10.1186/1471-2105-16-S4-S2
PMCID: PMC4347616

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