Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Lipid and Metabolite Deregulation in the Breast Tissue of Women Carrying BRCA1 and BRCA2 Genetic Mutations.

Radiology - 1 Jun 2015

Ramadan Saadallah, Arm Jameen, Silcock Judith, Santamaria Gorane, Buck Jessica, Roy Michele, Leong Kin Men, Lau Peter, Clark David, Malycha Peter, Mountford Carolyn

Abstract excerpt

PURPOSE: To use localized correlated spectroscopy (COSY) to assess for an altered biochemical state or states in breast tissue of women with BRCA gene mutations that potentially constitute preinvasive conditions. MATERIALS AND METHODS: Institutional review board approval was obtained. Participants provided written informed consent. In vivo localized COSY images were recorded at 3 T in the breast tissue of women...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Breast
Share to BRCA1 gene

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to BRCA2 gene

Share to Genes, BRCA1

Share to Genes, BRCA2

Share to Lipid Metabolism

Share to Mutation

Share to Spectrum Analysis

Source

Identifiers

PMID: 25734415
DOI: 10.1148/radiol.15140967

Genes

BRCA2
BRCA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Lipid and Metabolite Deregulation in the Breast Tissue of Women Carrying BRCA1 and BRCA2 Genetic Mutations.PMID 25734415Read ↗

In vivo assignment of methylmalonic acid in breast tissue using 2D MRS and relationship with breast density, menopausal status and cancer risk.Semantic proximity Read ↗

Enhanced Spectral Resolution for Correlated Spectroscopic Imaging Using Inner-Product and Covariance Transform: A Pilot Analysis of Metabolites and Lipids in Breast Cancer In VivoSemantic proximity Read ↗

Development of spatially-resolved lipidomic methods for cancer diagnosticsSemantic proximity Read ↗

Spatially resolved metabolic phenotyping of breast cancer by desorption electrospray ionization mass spectrometry.Semantic proximity Read ↗

The lipid-reactive oxygen species phenotype of breast cancer. Raman spectroscopy and mapping, PCA and PLSDA for invasive ductal carcinoma and invasive lobular carcinoma. Molecular tumorigenic mechanisms beyond Warburg effect.Semantic proximity Read ↗

Characterization of breast cancers and therapy response by MRS and quantitative gene expression profiling in the choline pathway.Semantic proximity Read ↗

The lipid phenotype of breast cancer cells characterized by Raman microspectroscopy: towards a stratification of malignancy.Semantic proximity Read ↗

Post-Radiotherapy Changes in Circulating Dodecanoic Acid Identify Metabolic Phenotypes Associated with Recurrence in Breast Cancer.Semantic proximity Read ↗

Post-Radiotherapy Changes of Circulating Dodecanoic Acid Identify Metabolic Phenotypes Associated with Recurrence in Breast CancerSemantic proximity Read ↗

Rapid Profiling of Isomeric Unsaturated Lipids Through Online Photochemical Derivatization of C=C BondsSemantic proximity Read ↗

In vivo MR spectroscopic imaging of polyunsaturated fatty acids (PUFA) in healthy and cancerous breast tissues by selective multiple‐quantum coherence transfer (Sel‐MQC): A preliminary studySemantic proximity Read ↗

Abnormal Choline Phospholipid Metabolism in Breast and Ovary Cancer:Molecular Bases for Noninvasive Imaging ApproachesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.