Article
Use of genome-wide heterospecific single-nucleotide polymorphisms to estimate linkage disequilibrium in rhesus and cynomolgus macaques.
Comparative medicine - 1 Feb 2015
Ng Jillian, Trask Jessica Satkoski, Houghton Paul, Smith David G, Kanthaswamy Sree
Abstract excerpt
Rhesus and cynomolgus macaques are frequently used in biomedical research, and the availability of their reference genomes now provides for their use in genome-wide association studies. However, little is known about linkage disequilibrium (LD) in their genomes, which can affect the design and success of such studies. Here we studied LD by using 1781 conserved single-nucleotide polymorphisms (SNPs) in 183 rhesus...
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