Article
Relationship between clinicopathological features and HIF-2α in gastric adenocarcinoma.
Genetics and molecular research : GMR - 13 Feb 2015
Li N, Wang H X, Qin C, Wang X H, Han F Y
Abstract excerpt
Hypoxia influences tumor growth by inducing angiogenesis and genetic alterations. Hypoxia-inducible factor-2α (HIF-2α) plays an essential role in oxygen homeostasis. Expression of HIF-2α-inducible genes is associated with tumor progression. In this study, we investigated this correlation immunohistochemically and using quantitative reverse transcription-polymerase chain reaction to examine various clinical and...
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