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Article

Epigenetic heredity: RNA-mediated modes of phenotypic variation.

Annals of the New York Academy of Sciences - 1 Apr 2015

Rassoulzadegan Minoo, Cuzin François

Abstract excerpt

In addition to the Mendelian mutations, several instances of heritable phenotypic variation have been reported. We have observed, in mice, a role for sperm RNAs in the induction of such stable phenotypic variation. When experimentally transferred by RNA microinjection into fertilized mouse eggs, the noncoding RNAs homologous in sequence to the target locus are efficient inducers of variation at the...

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PMID: 25726734
DOI: 10.1111/nyas.12694

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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