Article
CCL22 16C/a genetic variation is not associated with breast carcinoma in Southern Iranian population.
Iranian journal of immunology : IJI - 1 Dec 2012
Erfani Nasrollah, Moghaddasi-Sani Faezeh, Razmkhah Mahboubeh, Haghshenas Mohammad Reza, Talei Abdolrasoul, Ghaderi Abbas
Abstract excerpt
BACKGROUND: CCL22/MDC is a CC chemokine with a critical role in regulation of the immune balance in physiological condition. CCL22/CCR-4 ligation has been documented to participate in the migration of regulatory T (Treg) cells and Th2 lymphocytes to the site of breast tumors; circumstances that are known to be associated with poor prognosis. OBJECTIVE: To investigate the association of a single nucleotide...
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