Article
The combined use of cytokine-induced killer cells and cyclosporine a for the treatment of aplastic anemia in a mouse model.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research - 1 May 2015
Liu Shousheng, Wang Xiaopai, Lu Ying, Xiao Jianhong, Liang Jiayi, Zhong Xueyun, Chen Yunxian
Abstract excerpt
In this study, we investigated the combined use of cytokine-induced killer (CIK) cells and cyclosporine A (CsA) to treat a mouse model of aplastic anemia (AA). CIK cells were cultured and injected alone or in combination with CsA into mice that had previously been induced into AA by busulfan and mouse interferon-γ (IFN-γ). The CIK cell-treated group had a survival rate of 55%, which was similar to the 60%...
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