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Article

Prevalence and significance of two major inherited thrombophilias in infective endocarditis.

Internal and emergency medicine - 1 Aug 2015

Durante-Mangoni Emanuele, Iossa Domenico, Molaro Rosa, Andini Roberto, Mattucci Irene, Malgeri Umberto, Albisinni Rosina, Utili Riccardo

Abstract excerpt

The pathogenesis of infective endocarditis (IE) involves activation of the haemostasis system at the site of endocardial defects. Whether prothrombotic conditions are associated with IE by enhancing early vegetation formation is unknown. In this study, we assess the prevalence and clinical significance of two major conditions associated with thrombophilia in patients with IE. Mutations G20210A of the prothrombin...

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PMID: 25711313
DOI: 10.1007/s11739-015-1214-8

Genes

PTH

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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