Article
Hypercoagulation detected by routine and global laboratory hemostasis assays in patients with infective endocarditis.
PloS one - 1 Jan 2021
Koltsova Ekaterina M, Sorokina Maria A, Pisaryuk Alexandra S, Povalyaev Nikita M, Ignatova Anastasia A, Polokhov Dmitry M, Kotova Elizaveta O, Balatskiy Alexander V, Ataullakhanov Fazoil I, Panteleev Mikhail A, Kobalava Zhanna D, Balandina Anna N
Abstract excerpt
BACKGROUND: Coagulation system is heavily involved into the process of infective endocarditis (IE) vegetation formation and can facilitate further embolization. In this study we aimed to assess the coagulation and platelet state in IE implementing a wide range of standard and global laboratory assays. We also aim to determine whether prothrombotic genetic polymorphisms play any role in embolization and mortality...
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