Article
Genetic variant of IL28B rs12979860, as predictive marker of interferon-based therapy in Pakistani population.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica - 1 Apr 2015
Imran Muhammad, Manzoor Sobia, Azam Sikandar, Resham Saleha
Abstract excerpt
Hepatitis C virus (HCV) genotypes and genetic variants of interleukin 28B (IL28B) are significantly associated with interferon plus ribavirin treatment of HCV infection. We investigated the distribution of HCV genotypes and single-nucleotide polymorphisms (SNPs) of IL28B (rs12979860 and rs8099917) in Pakistani population. IL28B genotyping was performed by allele-specific PCR and restriction fragment length...
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