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Article

The G allele of CaSR R990G polymorphism increases susceptibility to urolithiasis and hypercalciuria: evidences from a comprehensive meta-analysis.

BioMed research international - 1 Jan 2015

Liu Kang, Wang Xiaolan, Ye Jiaxin, Qin Chao, Shao Pengfei, Zhang Wei, Li Jie, Yin Changjun

Abstract excerpt

BACKGROUND: The calcium-sensing receptor gene (CaSR) is a candidate to explain urolithiasis. A number of case-control studies were conducted to investigate associations between CaSR polymorphisms with risks of hypercalciuria and urolithiasis in humans. But the results were still inconsistent. METHODS: A meta-analysis was performed to address this issue. Crude odds ratios (ORs) with 95% confidence intervals (CIs)...

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Identifiers

PMID: 25705702
DOI: 10.1155/2015/958207
PMCID: PMC4331470

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