Article
The endosomal pathway in Parkinson's disease.
Molecular and cellular neurosciences - 1 May 2015
Perrett Rebecca M, Alexopoulou Zoi, Tofaris George K
Abstract excerpt
Parkinson's disease is primarily a movement disorder with predilection for the nigral dopaminergic neurons and is often associated with widespread neurodegeneration and diffuse Lewy body deposition. Recent advances in molecular genetics and studies in model organisms have transformed our understanding of Parkinson's pathogenesis and suggested unifying biochemical pathways despite the clinical heterogeneity of the...
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