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Article

Diquat causes caspase-independent cell death in SH-SY5Y cells by production of ROS independently of mitochondria

18 Feb 2015

Abstract excerpt

Evidence indicates that Parkinson's disease (PD), in addition to having a genetic aetiology, has an environmental component that contributes to disease onset and progression. The exact nature of any environmental agent contributing to PD is unknown in most cases. Given its similarity to paraquat, an agrochemical removed from registration in the EU for its suspected potential to cause PD, we have investigated the...

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PMID: 25693864
DOI: 10.1007/s00204-015-1453-5

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