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Chromosome Organization and Replisome Dynamics in Mycobacterium smegmatis

18 Feb 2015

Abstract excerpt

UNLABELLED: Subcellular organization of the bacterial nucleoid and spatiotemporal dynamics of DNA replication and segregation have been studied intensively, but the functional link between these processes remains poorly understood. Here we use quantitative time-lapse fluorescence microscopy for single-cell analysis of chromosome organization and DNA replisome dynamics in Mycobacterium smegmatis. We report that...

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PMID: 25691587
DOI: 10.1128/mbio.01999-14

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