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Article

SMC is recruited to <i>oriC</i> by ParB and promotes chromosome segregation in <i>Streptococcus pneumoniae</i>

9 Jun 2011

Abstract excerpt

Segregation of replicated chromosomes is an essential process in all organisms. How bacteria, such as the oval-shaped human pathogen Streptococcus pneumoniae, efficiently segregate their chromosomes is poorly understood. Here we show that the pneumococcal homologue of the DNA-binding protein ParB recruits S. pneumoniae condensin (SMC) to centromere-like DNA sequences (parS) that are located near the origin of...

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PMID: 21651626
DOI: 10.1111/j.1365-2958.2011.07722.x

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