Article
CTX-M-27- and CTX-M-14-producing, ciprofloxacin-resistant Escherichia coli of the H30 subclonal group within ST131 drive a Japanese regional ESBL epidemic.
The Journal of antimicrobial chemotherapy - 1 Jan 2015
Matsumura Yasufumi, Johnson James R, Yamamoto Masaki, Nagao Miki, Tanaka Michio, Takakura Shunji, Ichiyama Satoshi
Abstract excerpt
OBJECTIVES: The global increase in ESBL-producing Escherichia coli is associated with the ST131 clonal group, especially its CTX-M-15-producing H30Rx subset. To understand the rapid spread of ESBL-producing E. coli in Japan, we investigated the molecular epidemiology and ESBL-associated genetic environments of Japanese ST131 isolates. METHODS: Between 2001 and 2012, 1079 ESBL-producing E. coli isolates were...
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