Article
Low frequency of EGFR mutations in pleural mesothelioma patients, Cologne, Germany.
Applied immunohistochemistry & molecular morphology : AIMM - 1 Feb 2015
Schildgen Verena, Pabst Olga, Tillmann Ramona-Liza, Lüsebrink Jessica, Schildgen Oliver, Ludwig Corinna, Brockmann Michael, Stoelben Erich
Abstract excerpt
EGFR mutations were previously found in patients suffering from peritoneal mesothelioma but have not yet been described in pleural mesothelioma. The aim of the present study was the identification of EGFR mutations in patients suffering from pleural mesothelioma. Pleural mesothelioma tissue from 31 patients was used to analyze possible mutations in the EGFR gene comprising the exons 18-21 with the codons 719,...
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