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Article

Correlation of FLT3 mutations with expression of CD7 in acute myeloid leukemia.

Applied immunohistochemistry & molecular morphology : AIMM - 1 Feb 2015

Baqai Junaid, Crisan Domnita

Abstract excerpt

FLT3 mutations are common in acute myeloid leukemia (AML), particularly in cases with normal karyotype. Internal tandem duplication (ITD) and also point mutations affecting aspartic acid 835 (D835) are reported. A previous study demonstrated aberrant expression of CD7 on blasts in de novo AML cases with FLT3/ITD mutations. Our study goals are to expand the evaluation of this association to a larger group of...

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Share to Antigens, CD7
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Leukemic

Share to Leukemia, Myeloid, Acute

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Source

Identifiers

PMID: 25679063
DOI: 10.1097/PDM.0000000000000034

Genes

FLT3
NPM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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