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Article

CD123 immunohistochemical expression in acute myeloid leukemia is associated with underlying FLT3-ITD and NPM1 mutations.

Applied immunohistochemistry & molecular morphology : AIMM - 1 May 2013

Rollins-Raval Marian, Pillai Raju, Warita Katsuhiko, Mitsuhashi-Warita Tomoko, Mehta Rohtesh, Boyiadzis Michael, Djokic Miroslav, Kant Jeffrey A, Roth Christine G

Abstract excerpt

FLT3-ITD and NPM1 mutation testing in acute myeloid leukemia (AML) plays an important role in prognostic risk stratification, especially within the intermediate cytogenetic risk group. Molecular studies require adequate fresh material and are typically performed on a dedicated aspirate specimen, which may not be available in all cases. Prior flow cytometric studies have suggested an association between CD123...

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Source

Identifiers

PMID: 22914610
DOI: 10.1097/PAI.0b013e318261a342

Genes

FLT3
NPM1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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CD123 immunohistochemical expression in acute myeloid leukemia is associated with underlying FLT3-ITD and NPM1 mutations.PMID 22914610Read ↗

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