Article
HLA-B alleles B*15:01 and B*15:02: opposite association with hepatitis C virus infection in Chinese voluntary blood donors.
Intervirology - 1 Jan 2015
Xiong Huaping, Huang Jieting, Rong Xia, Zhang Ming, Huang Ke, Xu Ru, Wang Min, Li Chengyao, Liao Qiao, Xia Wenjie, Luo Guangping, Ye Xin, Lu Ling, Fu Yongshui, Guo Tai, Nelson Kenrad
Abstract excerpt
BACKGROUND: Although human leukocyte antigens (HLA) have been shown in association with the outcomes of hepatitis C virus (HCV) infection among different ethnic groups, such studies remain absent in China, where the HCV prevalence is higher than the global average. METHODS: In this study, 426 HCV-infected and 709 uninfected blood donors were analyzed, among whom the HLA alleles were sequenced using a...
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