Article
A metaproteomics approach to elucidate host and pathogen protein expression during catheter-associated urinary tract infections (CAUTIs).
Molecular & cellular proteomics : MCP - 1 Apr 2015
Lassek Christian, Burghartz Melanie, Chaves-Moreno Diego, Otto Andreas, Hentschker Christian, Fuchs Stephan, Bernhardt Jörg, Jauregui Ruy, Neubauer Rüdiger, Becher Dörte, Pieper Dietmar H, Jahn Martina, Jahn Dieter, Riedel Katharina
Abstract excerpt
Long-term catheterization inevitably leads to a catheter-associated bacteriuria caused by multispecies bacterial biofilms growing on and in the catheters. The overall goal of the presented study was (1) to unravel bacterial community structure and function of such a uropathogenic biofilm and (2) to elucidate the interplay between bacterial virulence and the human immune system within the urine. To this end, a...
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