High Individuality of Respiratory Bacterial Communities in a Large Cohort of Adult Cystic Fibrosis Patients under Continuous Antibiotic Treatment

Abstract excerpt

BACKGROUND: Routine clinical diagnostics of CF patients focus only on a restricted set of well-known pathogenic species. Recent molecular studies suggest that infections could be polymicrobial with many bacteria not detected by culture-based diagnostics. METHODOLOGY AND PRINCIPAL FINDINGS: A large cohort of 56 adults with continuous antibiotic treatment was studied and different microbial diagnostic methods were...

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